Patients contact

For questions and contact with other patients

Contact with patients

News & Events

Our latest news & events

News & Events

Support us

We need your support!

Support us

About PLN Genetic Heart Disease

For our heart to beat, calcium ions in the heart muscle cells are important. The phospholamban (PLN) protein plays an important role in the calcium balance of the heart muscle cells.

Heart disease is caused by a loss of cardiomyocytes (heart muscle cells), usually because of a heart attack or weakening of the cardiac muscle cells. Heart contractions and the ability to pump blood through our bodies depend on well orchestrated calcium movements in and out of the cell. The PLN (phospholamban) gene is a key regulator of the pump that controls calcium cycling. Scientific names for this PLN gene mutation are c.40_42del AGA and PLN.Arg14del.

More about PLN Support Us

Visit our social channels

All the most relevant information directly on your timeline!

Why our foundation?

  • Conduct scientific research projects
  • Stimulate partnership with PLN Institutes
  • Intensify hospitals & medical centers network
  • Inform about latest PLN research developments
  • Support PLN patients and family members
About our foundation

Subscribe to our PLN related newsletter

Receive the most relevant PLN information directly into your mailbox... sign up for our newsletter!

You are here: Home