Press Information

Raising awareness about PLN is a collaborative effort, and the media plays a crucial role in reaching more people and informing carriers in a timely manner. We would like to connect with you to develop articles, podcasts, or other forms of content. Our team is here to assist and provide insights.

Important Information:

Facts:

Objectives:

Current Status:

Currently, there is no curative treatment for the PLN mutation. Treatments are tailored to each patient to alleviate symptoms. Some individuals receive medications, while others may need an Implantable Cardioverter Defibrillator (ICD) to address rhythm disturbances. In extreme cases, a left ventricular assist device (LVAD) or ultimately a heart transplant may be necessary.

Mutated phospholamban proteins (PLN) are produced from the mutated PLN gene in the DNA. Many potential PLN therapies being researched target specific points in this production process. For example, researchers are investigating ways to “repair” the mutation in the DNA using DNA editing techniques such as CRISPR-Cas or Prime Editing.

There are also explorations of possibilities to intercept the faulty mRNA using short interfering RNA, short hairpin RNA, or antisense RNA. This could prevent the production of the faulty PLN protein. To learn more about PLN and its origins, click here.

In the press earlier (mostly Dutch publications):

Logo & Visual Identity

If you require graphic elements for an article, podcast, or video, we are happy to provide them. Below are the color codes of our corporate identity, and you can download our logo.

#E64023

#0097D6

#07425B

#101C39

#e9e9e9

#555555

Need anything else?

Carriers

Our foundation is founded for and by carriers. Therefore, we are always in contact with carriers across the country who are willing to share their stories for interviews or research.

Angles

PLN influences your life, so we can always brainstorm various angles for publications. Consider angles related to pregnancy or lifestyle.

Visuals

If you need visual materials for a publication, we are pleased to provide them. In consideration of privacy, we may provide visual materials in consultation with the person depicted.

Contact

Submit Press Inquiry

Would you like to submit a press inquiry? We are pleased to connect with you. You can also use this form to request additional information about PLN. Our colleagues Marise & Nikki will contact you to schedule an appointment with Chairman Pieter Glijnis.