How are cardiac arrhythmias actually caused? We know that cardiac arrhythmias occur in PLN and that PLN regulates calcium. Calcium is important for the conversion of an electrical signal into…
In a series of three articles, we will discuss the mechanism behind cardiac arrhythmias. In these three articles, we discuss three studies in which cardiac arrhythmias were investigated at the…
Original article: Zwaag Van der, 2012, Eur. Original article: Zwaag Van der, 2013, Neth. In a previous article, we described the discovery of PLN-R14del in Greek cardiac patients. In 2009,…
Original article: Haghighi, 2006, PNAS A mutation in the human phospholamban gene, deleting arginine 14, results in lethal hereditary cardiomyopathy The first scientific article on the R14del mutation appeared in…
